Evaluasi Kadar Oksibenzon dalam Sediaan Lotion Tabir Surya yang Beredar di Pasar Modern Menggunakan Spektrofotometri Ultraviolet

Authors

  • Herman Widjaja Program Studi Farmasi, Fakultas Farmasi, Universitas 17 Agustus 1945 Jakarta, Jalan Sunter Permai Raya, Jakarta Utara, Daerah Khusus Ibukota Jakarta 14350, Indonesia
  • Arnoldus Christian Waani Program Studi Farmasi, Fakultas Farmasi, Universitas 17 Agustus 1945 Jakarta, Jalan Sunter Permai Raya, Jakarta Utara, Daerah Khusus Ibukota Jakarta 14350, Indonesia

DOI:

https://doi.org/10.36312/educatoria.v6i2.1252

Keywords:

Lotion, Oxybenzone, Ultraviolet Spectrophotometry, Sunscreen

Abstract

Cosmetics are a mixture of chemical compounds from natural and synthetic materials used for skin care. One of the widely used cosmetic products is sunscreen which functions to protect the skin from Ultraviolet (UV) radiation. Oxybenzone is an active ingredient commonly used as a UV absorber, but its use is limited by regulations due to potential side effects. This study aims to evaluate the levels of oxybenzone in commercial sunscreen lotions circulating in the modern market using the UV-Vis spectrophotometry method. The analysis was carried out at a maximum wavelength (λmax) of 288 nm with the standard curve method, after optimization of the operating time. Measurements were carried out in replication to ensure data validity. The study samples consisted of three commercial sunscreen lotion products widely circulating in the modern market. The results of the analysis showed that the average oxybenzone levels in sample A were 6.7 ± 0.0107%, sample B was 6.03 ± 0.0104%, and sample C was 2.34 ± 0.0060%. All samples remained below the maximum limit set by the Indonesian Food and Drug Monitoring Agency (BPOM), which is 10%. These results indicate that the tested products still meet the safety requirements for the active ingredient oxybenzone. These findings underscore the importance of regular cosmetic quality control to ensure regulatory compliance and consumer safety.

Downloads

Download data is not yet available.

References

Andayani, R., Andira, R. P., & Armin, F. (2024). Analysis of Oxybenzone in Sunscreen Lotions Using Validated Reversed Phase TLC-Densitometry. Indonesian Journal of Pharmaceutical Science and Technology (IJPST), 11(3), 323-331. https://doi.org/10.24198/ijpst.v11i3.43555

Andrews, D. Q., Rauhe, K., Burns, C., Spilman, E., Temkin, A. M., Perrone-Gray, S., Naidenko, O. V., & Leiba, N. (2021). Laboratory Testing of Sunscreens on the U.S. Market Finds Lower In Vitro SPF Values Than on Labels and Even Less UVA Protection. Photodermatology Photoimmunology and Photomedicine, 38(4), 224-232. https://doi.org/10.1111/phpp.12738

Downs, C. A., Kramarsky-Winter, E., Segal, R., Fauth, J., Knutson, S., Bronstein, O., Ciner, F. R., Jeger, R., Lichtenfeld, Y., Woodley, C. M., Pennington, P., Cadenas, K., Kushmaro, A., & Loya, Y. (2016). Toxicopathological Effects of the Sunscreen UV Filter, Oxybenzone (Benzophenone-3), on Coral Planulae and Cultured Primary Cells and Its Environmental Contamination in Hawaii and the U.S. Virgin Islands. Archives of Environmental Contamination and Toxicology, 70(2), 265-288. https://doi.org/10.1007/s00244-015-0227-7

Draelos, Z. D. (2018). Cosmetic Dermatology: Products and Procedures. Hoboken: Wiley-Blackwell.

Matta, M. K., Florian, J., Zusterzeel, R., Pilli, N. R., Patel, V., Volpe, D. A., Yang, Y., Oh, L., Bashaw, E., Zineh, I., Sanabria, C., Kemp, S., Godfrey, A., Adah, S., Coelho, S., Wang, J., Furlong, L. A., Ganley, C., Michele, T., & Strauss, D. G. (2020). Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial. JAMA, 323(3), 256-267. https://doi.org/10.1001/jama.2019.20747

Nitulescu, G., Lupuliasa, D., Adam-Dima, I., & Nitulescu, G. M. (2023). Ultraviolet Filters for Cosmetic Applications. Cosmetics, 10(4), 101. https://doi.org/10.3390/cosmetics10040101

Peraturan Badan Pengawas Obat dan Makanan Republik Indonesia Nomor 23 Tahun 2019 tentang Persyaratan Teknis Bahan Kosmetika. 2019. Jakarta: Badan Pengawas Obat dan Makanan Republik Indonesia.

Pfeifer, G. P. (2020). Mechanisms of UV-Induced Mutations and Skin Cancer. Genome Instab. Dis., 1, 99-113. https://doi.org/10.1007/s42764-020-00009-8

Rahmawati, R. (2019). Penetapan Kadar Oksibenzon dalam Kosmetika Tabir Surya. Skripsi. Universitas Lambung Mangkurat.

Wu, F., Tan, S., Fang, Z., Deng, J., He, Z., Huang, C., Au, C., & Yi, B. (2022). Substituent Effects on the Ultraviolet Absorption Properties of 2,4-Dihydroxy Dibenzophenone. Molecules, 27(23), 8169. https://doi.org/10.3390/molecules27238169

Young, A. R., Claveau, J., & Rossi, A. B. (2017). Ultraviolet Radiation and the Skin: Photobiology and Sunscreen Photoprotection. Journal of the American Academy of Dermatology, 76(3), S100-S109. https://doi.org/10.1016/j.jaad.2016.09.038

Downloads

Published

2026-04-30

How to Cite

Widjaja, H., & Waani, A. C. (2026). Evaluasi Kadar Oksibenzon dalam Sediaan Lotion Tabir Surya yang Beredar di Pasar Modern Menggunakan Spektrofotometri Ultraviolet. Educatoria : Jurnal Ilmiah Ilmu Pendidikan, 6(2), 441–447. https://doi.org/10.36312/educatoria.v6i2.1252

Issue

Section

Articles